Dynamic 1D search and processive nucleosome translocations by RSC and ISW2 chromatin remodelers

The Wu lab utilized optical tweezers and two-color single-particle imaging to examine the Brownian diffusion of RSC and ISW2 on unbound DNA and scattered nucleosome arrays.

Various members of the Wu lab recently published a ground-breaking article on March 18, 2024 that can be found here. The article was published in eLife Sciences.