Dynamic 1D search and processive nucleosome translocations by RSC and ISW2 chromatin remodelers

Dynamic 1D search and processive nucleosome translocations by RSC and ISW2 chromatin remodelers

The Wu lab utilized optical tweezers and two-color single-particle imaging to examine the Brownian diffusion of RSC and ISW2 on unbound DNA and scattered nucleosome arrays.

Various members of the Wu lab recently published a ground-breaking article on March 18, 2024 that can be found here. The article was published in eLife Sciences.